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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D19
All Species:
31.82
Human Site:
Y354
Identified Species:
58.33
UniProt:
Q8N5T2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N5T2
NP_060787.2
526
60268
Y354
G
K
L
G
L
E
E
Y
A
V
F
Y
P
P
N
Chimpanzee
Pan troglodytes
XP_001166746
526
60188
Y354
G
K
L
G
L
E
E
Y
A
V
F
Y
P
P
N
Rhesus Macaque
Macaca mulatta
XP_001084301
526
60205
Y354
G
K
L
G
L
E
E
Y
A
V
F
Y
P
P
N
Dog
Lupus familis
XP_536268
525
59882
Y353
G
K
L
G
L
E
E
Y
A
V
F
Y
P
P
N
Cat
Felis silvestris
Mouse
Mus musculus
NP_653100
526
60385
Y354
G
K
L
G
L
E
E
Y
A
V
F
Y
P
P
N
Rat
Rattus norvegicus
NP_001099478
526
60309
Y354
G
K
L
G
L
E
E
Y
A
V
F
Y
P
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514213
547
62259
Y375
G
K
L
G
M
E
E
Y
A
V
F
Y
P
P
N
Chicken
Gallus gallus
XP_420750
526
60176
Y354
G
K
L
G
I
E
E
Y
A
V
F
Y
P
P
N
Frog
Xenopus laevis
NP_001089246
527
60151
F355
G
K
L
G
L
E
E
F
A
V
S
Y
P
P
N
Zebra Danio
Brachydanio rerio
NP_956785
526
60133
C354
S
K
S
G
S
E
Q
C
A
V
V
Y
P
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608913
509
58458
K339
E
T
F
P
V
K
G
K
T
Y
E
G
P
P
S
Honey Bee
Apis mellifera
XP_623591
536
62028
N366
G
K
P
A
T
L
E
N
T
L
V
F
P
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001191986
401
45886
P238
E
F
A
V
V
Y
P
P
N
G
V
I
P
F
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
93.3
N.A.
97.3
97.7
N.A.
85.1
91.2
84.6
77.5
N.A.
39.9
43.2
N.A.
47.3
Protein Similarity:
100
100
100
95
N.A.
98.8
99.2
N.A.
89
95.8
93.1
87.2
N.A.
62.3
63
N.A.
61
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
86.6
60
N.A.
13.3
33.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
66.6
N.A.
33.3
53.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
77
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
0
0
0
0
77
77
0
0
0
8
0
0
0
0
% E
% Phe:
0
8
8
0
0
0
0
8
0
0
62
8
0
8
0
% F
% Gly:
77
0
0
77
0
0
8
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
85
0
0
0
8
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
70
0
54
8
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
77
% N
% Pro:
0
0
8
8
0
0
8
8
0
0
0
0
100
93
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
0
8
0
0
0
0
0
8
0
0
0
16
% S
% Thr:
0
8
0
0
8
0
0
0
16
0
0
0
0
0
0
% T
% Val:
0
0
0
8
16
0
0
0
0
77
24
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
62
0
8
0
77
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _